chemReactor BR


Basic glass pilot reactor and pilot plant


chemreactor - 15 - 100 liters pilot plant & kilo lab pharma glass reactor
chemReactor BR, 30 liter

Glass reactor: 15 / 30 / 60 / 100 liter
Pressure: -1.0 (FV) to +0.5 bar
Temperature: -60°C (-90°C) to +200°C
Material: Borosilicate glass 3.3 / glass lined steel / PTFE / PFA / Tantalum

  • Other setups are available.

Performance and reliability are key issues in the explosion proof design of Büchi glass reaction systems. The inert materials allow safe processing in an inert atmosphere of a wide range of solvents and acids in a completely sealed glass reaction system under full vacuum. Multiple chemical reaction steps are performed safely in the same setup. Processes can be easily improved by visually observing the reaction through the glass.

The BR type chemReactor is a basic pilot reactor system for chemical process development, scale-up, process simulation and kilo-scale cGMP  production in batch and semi-batch operation.

We offer complete solutions for chemical processing including accessories like sampling devices, pH probes, rectification columns with structured packings, process monitoring and control as well as auxiliary equipment like temperature control units, nutsch filters / dryers, scrubbers or mixing vessels.

Standard package


  • Jacketed full glass reactor
  • Multipurpose glass distillation overhead
  • Stainless steel frame, supporting flexible glass superstructure
  • ATEX Zone 1 (0) / CE / cGMP
  • CIP capable
  • FDA conform, highly corrosion resistant
  • Complete documentation

Standard options


  • Reactor lift for easy opening (vessel cleaning)
  • Tripple wall reactor vessel
  • Sampling device
  • pH monitoring and control
  • Gas introduction (Nitrogen purging and active gas)
  • Vacuum / exhaust piping
  • Additional feeders / receivers
  • Solid feeding
  • IQ / OQ / PQ

Reactor vessel


Jacketed glass reactor
  • Jacketed glass reactor 15 / 30 / 50 / 100 liter
  • Baffle with Pt100 temperature sensor
  • Flush mounted drain valve (zero dead volume)

ATEX stirrer drive


ATEX agitator drive, dry running
  • ATEX motor and adjustable transmission
  • ATEX dry running mechanical seal
  • Glass lined impeller stirrer

Glass dome / Glass lined cover plate


Glass dome - Glass lined steel cover plate
  • Glass cover dome (15 & 30 liter)
  • Glass lined steel cover (50 & 100 liter)
  • Fast-action closure for addition of solids
  • 8 connection nozzles

Distillation glass overhead


Distillation glass overhead
  • Feed vessel for liquid addition
  • Distillation column / vapor duct with pressure gauge and bursting disc
  • Spiral condenser with vacuum / exhaust connection
  • Receiver vessel for collection of distillate
  • Self-draining «büchiflex» glass piping

Typical applications


  • Vacuum distillation
  • Azeotropic distillation (phase separation)
  • Evaporation to any desired consistency
  • Multi-component reactions
  • Gas introduction into liquid phase
  • Extraction of multi phase mixture
  • Crystallization
  • Refluxing
  • Multiple chemical reactions liquid/liquid, liquid/solid
  • Low temperature chemistry
«büchiflex»

Büchi glass reactors are based on the modular «büchiflex» glass system. This unique flexible glass connection provides:

  • safety
  • economy
  • full tightness
  • clean processes

Büchiflex video


Flash is required!

Summing up